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Start GLUCOPHAGE 500 mg twice a day with meals

3 min read · Reviewed 5 October 2026, 08:06:51 UTC

Medically reviewed by Dr. Priya Natarajan, MD - Clinical pharmacology, Dublin

01500 mg with meals

The usual starting dose of GLUCOPHAGE tablets is 500 mg twice a day, given with meals. Gradual dose escalation may improve gastrointestinal tolerability. The 500 mg tablet with food is the labelled adult start on immediate-release tablets.

Before you start, stop, or change any medicine, speak with your prescriber or pharmacist. They hold your chart. This bin card does not. Open the bin disclaimer.

Sources

1. FDA / Glucophage (metformin) prescribing information

Checked against the current label and reviewed by Dr. Priya Natarajan. See Pick → Check → Tag → Bin.