01Cirrhosis after alcohol abuse
In 8 people whose cirrhosis followed alcohol abuse, mean elimination half-life was 3.38 hours. In 8 age- and weight-matched subjects without that liver disease, the mean was 1.11 hours. Mean total clearance in the cirrhotic group was about 70% lower.
Generic methocarbamol 750 mg x 30, GoodRx tablet table, 2026 board.
Generic methocarbamol 750 mg, thirty tablets - the strength used for the short courses described above, checked October 2026. GoodRx lists 750 mg x 30 at $29.94 average retail and $2.00 with a coupon. The 500 mg tablet is priced separately. Kaelis Med does not dispense.
02Plasma half-life
In healthy volunteers, the mean plasma elimination half-life of methocarbamol was 1 to 2 hours. In elderly volunteers the mean was 1.5 hours. In younger volunteers the mean was 1.1 hours. Plasma protein binding sat between 46% and 50%. The labeled indication is as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions.